An internal standard for the quantification of gallic acid
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Unlabeled Version(s)
11846Gallic Acid
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Gallic Acid-d2

Item No. 35132

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4,5-trihydroxy-benzoic-2,6-d2 acid
CAS Number
294660-92-7
Synonyms
  • 3,4,5-Trihydroxybenzoic Acid-d2
Molecular Formula
C7H4D2O5
Formula Weight
172.1
Purity
≥99% deutereated forms (d1-d2)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlDMSO:PBS (pH 7.2) (1:3): 0.25 mg/mlEthanol: 5 mg/ml
λmax
218, 273 nm
SMILES
OC(C([2H])=C1C(O)=O)=C(C(O)=C1[2H])O
InChi Code
InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)/i1D,2D
InChi Key
LNTHITQWFMADLM-QDNHWIQGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    Product Description

    Gallic acid-d2 is intended for use as an internal standard for the quantification of gallic acid (Item No. 11846) by GC- or LC-MS. Gallic acid is a phenol that has been found in C. sinensis and has diverse biological activities.1,2,3,4 It scavenges DPPH (Item No. 14805) and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM, respectively).1 Gallic acid (1-100 µM) reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings.2 In vivo, gallic acid (21.8 g/kg) inhibits morpholine- and sodium nitrite-induced adenocarcinoma formation in mice.3 It also inhibits passive cutaneous anaphylaxis in mice when administered at a dose of 50 mg/kg.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Cos, P., Hermans, N., Calomme, M., et al. Comparative study of eight well-known polyphenolic antioxidants. J. Pharm. Pharmacol. 55(9), 1291-1297 (2003).

    2. Ray, S.D., Guruprasad, K.N., and Laloraya, M.M. Antagonistic action of phenolic compounds on abscisic acid-induced inhibition of hypocotyl growth. J. Exp. Bot. 31(125), 1651-1656 (1980).

    3. Mirvish, S.S., Cardesa, A., Wallcave, L., et al. Induction of mouse lung adenomas by amines or ureas plus nitrite and by N-nitroso compounds: Effect of ascorbate, gallic acid, thiocyanate, and caffeine. J. Natl. Cancer Inst. 55(3), 633-636 (1975).

    4. Kar, K., Mohanta, P.K., Popli, S.P., et al. Inhibition of passive cutaneous anaphylaxis by compounds of Camellia sinensis. Planta Med. 42(1), 75-78 (1981).