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7-hydroxy Mitragynine

Item No. 13114

Synonyms
Synonyms
  • 9-methoxy Corynantheidine Hydroxyindolenine
  • 7-HMG
Technical Information
Formal Name
(αE,2S,3S,7aS,12bS)-3-ethyl-1,2,3,4,6,7,7a,12b-octahydro-7a-hydroxy-8-methoxy-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic acid, methyl ester
CAS Number
174418-82-7
Molecular Formula
C23H30N2O5
Formula Weight
Purity
≥98%
A crystalline solid
Ethanol: 5 mg/mlMethanol: 10 mg/ml
SMILES
O=C(OC)/C([C@H]1C[C@@]2([H])C3=NC4=CC=CC(OC)=C4[C@@]3(O)CCN2C[C@H]1CC)=C/OC
InChi Code
InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1
InChi Key
RYENLSMHLCNXJT-CYXFISRXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    7-hydroxy Mitragynine (Item No. 13114) is an analytical reference standard categorized as an opioid.1 7-hydroxy Mitragynine has been found in M. speciosa (Kratom in Thai) and is also an active metabolite of mitragynine (Item Nos. 18567 | 11151).2,3 This product is intended for research and forensic applications. For more information, please see Cayman's application note: Chromatographic Separation of 7-Hydroxy Mitragynine from Mitragynine Pseudoindoxyl.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takayama, H., Ishikawa, H., Kurihara, M., et alStudies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: Discovery of opioid agonists structurally different from other opioid ligands. J. Med. Chem. 45(9), 1949-1956 (2002).

    2. Ponglux, D., Wongseripipatana, S., Takayama, H., et alA new indole alkaloid, 7α-hydroxy-7H-mitragynine, from Mitragyna speciosa in thailand. Planta Med. 60(6), 580-581 (1994).

    3. Basiliere, S., and Kerrigan, S. Identification of metabolites and potential biomarkers of kratom in urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1140, 121971 (2020).

    Product Citations

    Vandeputte, M.M., Cannaert, A., and Stove, C.P. In vitro functional characterization of a panel of non‑fentanyl opioid new psychoactive substances. Arch. Toxicol. 94(11), 3819-3830 (2020).