A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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7-hydroxy Mitragynine (CRM)

A 1 mg/ml solution in 0.1 N ammonia in methanol

Item No. 45125

Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 9-methoxy Corynantheidine
  • 7-HMG
  • Hydroxyindolenine
  • 7-Hydroxymitragynine
Technical Information
Formal Name
(αE)-3-ethyl-1,2S,3S,4,6,7,7aS,12bs-octahydro-7a-hydroxy-8-methoxy-α-(methoxymethylene)-indolo[2,3-a]quinolizine-2-acetic acid, methyl ester
CAS Number
174418-82-7
Molecular Formula
C23H30N2O5
Formula Weight
414.5
Formulation (Request formulation change)
A 1 mg/ml solution in 0.1 N ammonia in methanol
SMILES
COC1=C2C(N=C3[C@]2(O)CCN4[C@@]3([H])C[C@H](/C(C(OC)=O)=C\OC)[C@H](CC)C4)=CC=C1
InChi Code
InChI=1S/C23H30N2O5/c1-5-14-12-25-10-9-23(27)20-17(7-6-8-19(20)29-3)24-21(23)18(25)11-15(14)16(13-28-2)22(26)30-4/h6-8,13-15,18,27H,5,9-12H2,1-4H3/b16-13+/t14-,15+,18+,23+/m1/s1
InChi Key
RYENLSMHLCNXJT-CYXFISRXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Dry ice in continental US; may vary elsewhere
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    1 mg

    $789

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    Product Description

    7-hydroxy Mitragynine (CRM) (Item No. 45125) is a certified reference material categorized as an opioid.1 7-hydroxy Mitragynine has been found in M. speciosa (Kratom in Thai) and is also an active metabolite of mitragynine (Item Nos. 18567 | 11151).2,3 This product is intended for research and forensic applications. For more information, please see Cayman's application note: Chromatographic Separation of 7-Hydroxy Mitragynine from Mitragynine Pseudoindoxyl.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takayama, H., Ishikawa, H., Kurihara, M., et al. Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: Discovery of opioid agonists structurally different from other opioid ligands. J. Med. Chem. 45(9), 1949-1956 (2002).

    2. Ponglux, D., Wongseripipatana, S., Takayama, H., et al. A new indole alkaloid, 7α-hydroxy-7H-mitragynine, from Mitragyna speciosa in thailand. Planta Med. 60(6), 580-581 (1994).

    3. Basiliere, S., and Kerrigan, S. Identification of metabolites and potential biomarkers of kratom in urine. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 1140, 121971 (2020).

    Product Citations

    Sheehan, D., Li, Y., Meckler, E., et al. Avoiding false identification of 7-hydroxymitragynine in kratom products using a multicriteria LC-MS confirmation. J. Am. Soc. Mass Spectrom. (2026).