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JWH 018 (exempt preparation)

Item № 13169
CAS № 209414-07-3
Purity ≥98%
product image
                (CAS 209414-07-3)

Formulation:  A solution in methanol

SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 mg $45.00 0.00
     10 mg $80.00 0.00
     25 mg $180.00 0.00

Pricing updated 2019-03-26. Prices are subject to change without notice.

Description
Features
  • This product has been formulated as an exempt preparation which meets criteria established by the US DEA
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
Synonyms
  • AM678

JWH 018 is a mildly selective agonist of the peripheral cannabinoid (CB2) receptor, derived from the aminoalkylindole WIN 55,212-2. The Ki values for binding central cannabinoid (CB1) and CB2 receptors are 9.0 and 2.94 nM, respectively, for a CB1:CB2 ratio of 3.06.1 Its effects on suppression of spontaneous activity, maximum possible antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats.2

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Technical Information
Formal Name
(1-pentyl-1H-indol-3-yl)-1-naphthalenyl-methanone
CAS Number
209414-07-3
Synonyms
  • AM678
Molecular Formula
C24H23NO
Formula Weight
341.5
Purity
≥98%
Formulation
A solution in methanol
λmax
219, 246, 315 nm
SMILES
CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc12
InChI Code
InChI=1S/C24H23NO/c1-2-3-8-16-25-17-22(20-13-6-7-15-23(20)25)24(26)21-14-9-11-18-10-4-5-12-19(18)21/h4-7,9-15,17H,2-3,8,16H2,1H3
InChI Key
JDNLPKCAXICMBW-UHFFFAOYSA-N
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - no special processing required. For larger quantities or alternate sizes, please contact sales.

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 1 year
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Additional Information

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References & Product Citations
Product Description References

1. Aung, M.M., Griffin, G., Huffman, J.W., et al. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding Drug Alcohol Depend. 60(2), 133-140 (2000).

2. Wiley, J.L., Compton, D.R., Dai, D., et al. Structure-activity relationships of indole- and pyrrole-derived cannabinoids Journal of Pharmacology and Experimental Therapeutics 285(3), 995-1004 (1998).

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