A non-hydrolyzable ATP analog

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Isomer(s)

38635 Adenosine-5'-O-(3-thiotriphosphate) (sodium salt) 38668 Rp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) (sodium salt) 38535 Rp-Adenosine-5'-O-(1-thiotriphosphate) (sodium salt) 38669 Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate) (sodium salt) 38536 Sp-Adenosine-5'-O-(1-thiotriphosphate) (sodium salt)

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Adenosine 5'-(γ-thio)-triphosphate (lithium salt)

Name: Adenosine 5'-(γ-thio)-triphosphate (lithium salt)
Brand: -

Item No. 14957

Adenosine 5'-(γ-thio)-triphosphate (lithium salt) (ATPγS, CAS Number: 93839-89-5)

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)

Technical Information

Formal Name

P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen diphosphate), tetralithium salt

CAS Number

93839-89-5

Synonyms

ATPγS

Molecular Formula

C₁₀H₁₂N₅O₁₂P₃S • 4Li

Formula Weight

547.0

Purity

≥90%

Formulation (Request formulation change)

A crystalline solid

Solubility(Learn about Variance in Solubility)

PBS (pH 7.2): 10 mg/ml

λ_max

259 nm

SMILES

O=P(OP(OP([O-])([O-])=S)([O-])=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1.[Li+].[Li+].[Li+].[Li+]

InChi Code

InChI=1S/C10H16N5O12P3S.4Li/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-24-28(18,19)26-29(20,21)27-30(22,23)31;;;;/h2-4,6-7,10,16-17H,1H2,(H,18,19)(H,20,21)(H2,11,12,13)(H2,22,23,31);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1

InChi Key

DWQFDOIBOYDYKH-KWIZKVQNSA-J

Shipping & Storage Information

Storage

-20°C

Shipping

Wet ice in continental US; may vary elsewhere

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

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Product Description

Adenosine 5'-(γ-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y₂ and P2Y₁₁ receptors (pEC₅₀ = 5.52 for P2Y₁₁).¹ It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs, and can serve as a substrate for the RNA-stimulated nucleotide hydrolysis and RNA unwinding activities of eukaryotic initiation factor-4A.^2,3,4

WARNING This product is not for human or veterinary use.

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