An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
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Norbuprenorphine

Item No. 15897

Restricted Product (Schedule II)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(αS,5α,7α)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol
CAS Number
78715-23-8
Molecular Formula
C25H35NO4
Formula Weight
413.6
Purity
≥98%
Formulation
A neat solid
SMILES
C[C@](C(C)(C)C)(O)[C@]1([H])[C@@]([C@@](OC2=C3C4=CC=C2O)([H])[C@@]3(CCN[C@]5([H])C4)[C@@]65C1)(CC6)OC
InChi Code
InChI=1S/C25H35NO4/c1-21(2,3)22(4,28)16-13-23-8-9-25(16,29-5)20-24(23)10-11-26-17(23)12-14-6-7-15(27)19(30-20)18(14)24/h6-7,16-17,20,26-28H,8-13H2,1-5H3/t16-,17-,20-,22+,23-,24+,25-/m1/s1
InChi Key
YOYLLRBMGQRFTN-IOMBULRVSA-N
Regulatory Information
DEA Schedule
II
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Norbuprenorphine (Item No. 15897) is an analytical reference material categorized as an opioid.1,2 It is a major metabolite of buprenorphine (Item Nos. 14025 | ISO60178). Norbuprenorphine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Iizuka, H., Shimada, A., and Yanagita, T. Pharmacological studies of buprenorphine and its major metabolite RX2007M. Jitchuken Zenrinsho Kenkyuho 7(3), 279-321 (1981).

    2. Cone, E.J., Gorodetzky, C.W., Yousefnejad, D., et al. The metabolism and excretion of buprenorphine in humans. Drug Metab. Dispos. 12(5), 577-581 (1984).

    Product Citations

    Vandeputte, M.M., Walton, S.E., Shuda, S.A., et al. Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs. Anal. Bioanal. Chem. (2023).