A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Norbuprenorphine (CRM)

A 100 μg/ml solution in methanol

Item No. 42206

Exempt Product (US)
Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(αS,5α,7α)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanol
CAS Number
78715-23-8
Molecular Formula
C25H35NO4
Formula Weight
413.6
Formulation
A 100 μg/ml solution in methanol
SMILES
C[C@](C(C)(C)C)(O)[C@]1([H])[C@@]([C@@](OC2=C3C4=CC=C2O)([H])[C@@]3(CCN[C@]5([H])C4)[C@@]65C1)(CC6)OC
InChi Code
InChI=1S/C25H35NO4/c1-21(2,3)22(4,28)16-13-23-8-9-25(16,29-5)20-24(23)10-11-26-17(23)12-14-6-7-15(27)19(30-20)18(14)24/h6-7,16-17,20,26-28H,8-13H2,1-5H3/t16-,17-,20-,22+,23-,24+,25-/m1/s1
InChi Key
YOYLLRBMGQRFTN-IOMBULRVSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $41

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    Product Description

    Norbuprenorphine (CRM) (Item No. 42206) is a certified reference material categorized as an opioid.1,2 Norbuprenorphine is a major active metabolite of buprenorphine (Item Nos. ISO60178 | 14025). Norbuprenorphine is regulated as a Schedule II compound in the United States. Norbuprenorphine (CRM) (Item No. 42206) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Iizuka, H., Shimada, A., and Yanagita, T. Pharmacological studies of buprenorphine and its major metabolite RX2007M. Jitchuken Zenrinsho Kenkyuho 7(3), 279-321 (1981).

    2. Cone, E.J., Gorodetzky, C.W., Yousefnejad, D., et al. The metabolism and excretion of buprenorphine in humans. Drug Metab. Dispos. 12(5), 577-581 (1984).