A natural phytosterol
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Stigmasterol

Item No. 18079

Technical Information
Formal Name
stigmasta-5,22E-dien-3β-ol
CAS Number
83-48-7
Synonyms
  • NSC 8095
Molecular Formula
C29H48O
Formula Weight
Purity
≥90%
A crystalline solid
DMF: 1 mg/mlDMSO: 0.1 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
SMILES
CC(C)[C@H](CC)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h8-10,19-21,23-27,30H,7,11-18H2,1-6H3/b9-8+/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
InChi Key
HCXVJBMSMIARIN-PHZDYDNGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Stigmasterol is a natural plant sterol that can be isolated from certain seed oils and herbs, including those used for therapeutic purposes.1,2 Dietary consumption of phytosterols, including stigmasterol, may have beneficial health effects in adults, particularly against cancer and ulceration.3,4,5 Alternatively, phytosterols may contribute to inflammation and intestinal failure-associated liver disease in young individuals.6

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mo, S., Dong, L., Hurst, J., et alQuantitative analysis of phytosterols in edible oils using APCI liquid chromatography-tandem mass spectrometry. Lipids 48(9), 949-956 (2013).

    2. Ganie, S.A., and Yadav, S.S. Holoptelea integrifolia (Roxb.) Planch: A review of its ethnobotany, pharmacology, and phytochemistry. Biomed. Res. Int. 2014(401213), 1-12 (2014).

    3. Awad, A.B., and Fink, C.S. Phytosterols as anticancer dietary components: Evidence and mechanism of action. J. Nutr. 130, 2127-2130 (2000).

    4. Ali, H., Dixit, S., Ali, D., et alIsolation and evaluation of anticancer efficacy of stigmasterol in a mouse model of DMBA-induced skin carcinoma. Drug. Des. Devel. Ther. 9, 2793-2800 (2015).

    5. Tovey, F.I. Role of dietary phospholipids and phytosterols in protection against peptic ulceration as shown by experiments on rats. World J. Gastroenterol. 21(5), 1377-1384 (2015).

    6. Mutanen, A., Nissinen, M.J., Lohi, J., et alSerum plant sterols, cholestanol, and cholesterol precursors associate with histological liver injury in pediatric onset intestinal failure. Am. J. Clin. Nutr. 100(4), 1085-1094 (2014).