A phytosterol with diverse biological activities
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β-Sitostenone

Item No. 36703

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
stigmast-4-en-3-one
CAS Number
1058-61-3
Synonyms
  • NSC 49082
Molecular Formula
C29H48O
Formula Weight
412.7
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 0.33 mg/mlEthanol: Slightly soluble
λmax
241 nm
SMILES
C[C@@]12[C@](CC[C@]2([H])[C@@H](CC[C@@H](CC)C(C)C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(CC3)=CC(CC4)=O)C
InChi Code
InChI=1S/C29H48O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h18-21,24-27H,7-17H2,1-6H3/t20-,21-,24+,25-,26+,27+,28+,29-/m1/s1
InChi Key
RUVUHIUYGJBLGI-XJZKHKOHSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $130

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    5 mg

    $484

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    10 mg

    $905

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    Cayman Chemical
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    Product Description

    β-Sitostenone is a phytosterol that has been found in A. occidentale and has diverse biological activities.1,2,3,4 It inhibits basal nitric oxide (NO) production in RAW 264.7 macrophages (IC50 = 15.9 µM).1 β-Sitostenone is active against T. evansi (IC50 = 150 nM).2 It reduces mean blood pressure in normotensive rats when administered at a dose of 2 mg/kg.3 β-Sitostenone (1.3 and 3 mg/kg) decreases blood glucose levels in dogs.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tewtrakul, S., and Subhadhirasakul, S. Effects of compounds from Kaempferia parviflora on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha productions in RAW264.7 macrophage cells. J. Ethnopharmacol. 120(1), 81-84 (2008).

    2. Nyunt, K.S., Elkhateeb, A., Tosa, Y., et al. Isolation of antitrypanosomal compounds from Vitis repens, a medicinal plant of Myanmar. Nat. Prod. Commun. 7(5), 609-610 (2012).

    3. Barla, A., Birman, H., Kültür, Ş., et al. Secondary metabolites from Euphorbia helioscopia and their vasodepressor activity. Turk. J. Chem. 30(3), 325-332 (2006).

    4. Alexander-Lindo, R.L., Morrison, E.Y.S.A., and Nair, M.G. Hypoglycaemic effect of stigmast-4-en-3-one and its corresponding alcohol from the bark of Anacardium occidentale (cashew). Phytother. Res. 18(5), 403-407 (2004).