An Analytical Reference Material
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  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
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6α-Naloxol

Item No. 22146

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • 6-hydroxy Naloxone
  • NLL
Technical Information
Formal Name
(5α,6α)-4,5-epoxy-17-(2-propen-1-yl)-morphinan-3,6,14-triol
CAS Number
20410-95-1
Molecular Formula
C19H23NO4
Formula Weight
329.4
Purity
≥98%
Formulation
A crystalline solid
SMILES
O[C@]12[C@]3(CCN(CC=C)[C@@H]2C4)[C@](OC5=C3C4=CC=C5O)([H])[C@@H](O)CC1
InChi Code
InChI=1S/C19H23NO4/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11/h2-4,13-14,17,21-23H,1,5-10H2/t13-,14+,17-,18-,19+/m0/s1
InChi Key
HMWHERQFMBEHNG-AQQQZIQISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    6α-Naloxol (Item No. 22146) is an analytical reference material categorized as an opioid metabolite.1 It is an active metabolite of naloxone (Item No. ISO60191 | 15594) that has approximately the same binding affinity as naloxone for µ- and δ-opioid receptors.1 This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, D., Raehal, K.M., Bilsky, E.J., et al. Inverse agonists and neutral antagonists at µ opioid receptor (MOR): Possible role of basal receptor signaling in narcotic dependence. J. Neurochem. 77(6), 1590-1600 (2001).