A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
Related Products
Active Metabolite(s)
221466α-Naloxol 221486β-Naloxol
Reference Material(s)
15594Naloxone (hydrochloride)
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Naloxone (hydrochloride) (CRM)

A 1 mg/ml solution in methanol

Item No. ISO60191

Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • N-Allyldihydro-14-hydroxynormorphinone
  • NIH 7890
Technical Information
Formal Name
(5α)-4,5-epoxy-3,14-dihydroxy-17-(2-propen-1-yl)-morphinan-6-one, monohydrochloride
CAS Number
357-08-4
Molecular Formula
C19H21NO4 • HCl
Formula Weight
363.8
Formulation
A 1 mg/ml solution in methanol
SMILES
O[C@]12[C@]3(CCN(CC=C)[C@@H]2C4)[C@](OC5=C3C4=CC=C5O)([H])C(CC1)=O.Cl
InChi Code
InChI=1S/C19H21NO4.ClH/c1-2-8-20-9-7-18-15-11-3-4-12(21)16(15)24-17(18)13(22)5-6-19(18,23)14(20)10-11;/h2-4,14,17,21,23H,1,5-10H2;1H/t14-,17+,18+,19-;/m1./s1
InChi Key
RGPDIGOSVORSAK-STHHAXOLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $28

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    Product Description

    Naloxone (hydrochloride) (CRM) (Item No. ISO60191) is a certified reference material categorized as an opioid antagonist.1 Formulations containing naloxone have been used as antidotes for opioid overdose and the prevention of overdose. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Le Bourdonnec, B., Barker, W.M., Belanger, S., et al. Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as μ opioid receptor antagonists with improved opioid receptor selectivity profiles. Bioorg. Med. Chem. Lett. 18(6), 2006-2012 (2008).