A pyrimidine nucleoside
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Product Categories

Product Type

Biochemicals
Nucleotides/Nucleosides

Research Area

Cancer

5-Methyluridine

Item No. 27986

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
1463-10-1
Synonyms
  • Ribothymidine
  • Thymine riboside
Molecular Formula
C10H14N2O6
Formula Weight
258.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 16 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
267 nm
SMILES
O=C(NC(C(C)=C1)=O)N1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2
InChi Code
InChI=1S/C10H14N2O6/c1-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)18-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
InChi Key
DWRXFEITVBNRMK-JXOAFFINSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $36

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    Cayman Chemical
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    Product Description

    5-Methyluridine is a pyrimidine nucleoside and methylated form of uridine (Item No. 20300).1 It enhances the antitumor activity of 5-fluorouracil (Item No. 14416) in a mouse Erlich solid carcinoma model and a P388 murine leukemia model. It has been used to characterize the activity of a variety of enzymes, including uridine nucleosidase.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Tezuka, M., Chiba, Y., Okada, S., et al. Enhancement of antitumor activity of 5-fluorouracil by ribothymidine. J. Pharmacobiodyn. 9(8), 683-687 (1986).

    2. Magni, G., Fioretti, E., Ipata, P.L., et al. Bakers' yeast uridine nucleosidase. Purification, composition, and physical and enzymatic properties. The Journal of Biological Chemisty 250(1), 9-13 (1975).