An internal standard for the quantification of cytidine
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Unlabeled Version(s)
29602Cytidine
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Cytidine-d2

Item No. 36320

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
cytidine-5,6-d2
CAS Number
40632-25-5
Synonyms
  • β-D-Cytidine-d2
Molecular Formula
C9H11D2N3O5
Formula Weight
245.2
Purity
≥99% deuterated forms (d1-d2)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: solubleDMSO: soluble
SMILES
O[C@H]1[C@@](N2C(N=C(C([2H])=C2[2H])N)=O)([H])O[C@@H]([C@H]1O)CO
InChi Code
InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1/i1D,2D
InChi Key
UHDGCWIWMRVCDJ-SXFMXZDVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 µg

    $74

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    1 mg

    $118

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    5 mg

    $403

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    Product Description

    Cytidine-d2 is intended for use as an internal standard for the quantification of cytidine (Item No. 29602) by GC- or LC-MS. Cytidine is a pyrimidine nucleoside composed of ribose and a cytosine base.1 It forms complementary base pairs with the purine nucleoside guanosine (Item No. 27702) in DNA and RNA. Cytidine is a precursor of uridine (Item No. 20300) and can also be phosphorylated by uridine-cytidine kinase to form cytidine 5'-monophosphate (CMP; Item No. 35116).2,1 It rescues inhibition of proliferation induced by knockdown of CTP synthase 1 in T cells when used at a concentration of 200 µM.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Berg, J.M., Tymoczko, J.L., and Stryer, L. Nucleotide biosynthesis. Biochemistry (2002).

    2. Chabner, B.A., Johns, D.G., Coleman, C.N., et al. Purification and properties of cytidine deaminase from normal and leukemic granulocytes. J. Clin. Invest. 53(3), 922-931 (1974).

    3. Martin, E., Palmic, N., Sanquer, S., et al. CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation. Nature 510(7504), 288-292 (2014).