An internal standard for the quantification of aflatoxin M1
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Unlabeled Version(s)
11297Aflatoxin M1
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Aflatoxin M1-13C17

Item No. 31264

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6aR,9aR)-9a-hydroxy-4-(methoxy-13C)-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione-1,2,3,3a,3b,4,5,5a,6a,8,9,9a,9b,9c,11,11a-13C16
CAS Number
2707441-97-0
Synonyms
  • AFM1-13C17
Molecular Formula
[13C]17H12O7
Formula Weight
345.1
Purity
≥98%
Formulation (Request formulation change)
A 0.5 µg/ml solution in acetonitrile
Solubility(Learn about Variance in Solubility)
Acetonitrile: Soluble
SMILES
O=[13C]1[13C]2=[13C]([13CH2][13CH2][13C]2=O)[13C]3=[13C]([13C]([13C@@]([13CH]=[13CH]O4)(O)[13C@@]4([H])O5)=[13C]5[13CH]=[13C]3O[13CH3])O1
InChi Code
InChI=1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1,11+1,12+1,13+1,14+1,15+1,16+1,17+1
InChi Key
MJBWDEQAUQTVKK-QHFKDXDPSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Aflatoxin M1-13C17 (AFM1-13C17) is intended for use as an internal standard for the quantification of AFM1 (Item No. 11297) by GC- or LC-MS. AFM1 is an active metabolite of aflatoxin B1 (Item No. 11293).1 It induces hepatocyte hyperplasia and hepatocellular carcinoma tumor formation in rats when administered at a dose of 1 mg/animal. AFM1 (6 mg/kg) increases hepatic total lipid levels and inhibits hepatic mitochondrial and cytoplasmic protein synthesis in rats.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wogan, G.N., and Paglialunga, S. Carcinogenicity of synthetic aflatoxin M1 in rats. Food Cosmet. Toxicol. 12(3), 381-385 (1974).

    2. Pai, M.R., Bai, N.J., and Venkitasubramanian, T.A. Aflatoxin induced inhibition of protein synthesis. Toxicon 16(3), 283-287 (1978).