An internal standard for the quantification of L-cysteine
Related Products
Unlabeled Version(s)
33309L-Cysteine
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L-Cysteine-15N-d3

Item No. 34838

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
L-cysteine-2,3,3-d3-15N
CAS Number
1795787-05-1
Synonyms
  • L-Cys-15N-d3
  • L-(+)-Cysteine-15N-d3
  • (R)-Cysteine-15N-d3
Molecular Formula
C3H4D3[15N]O2S
Formula Weight
125.2
Purity
≥99% deuterated forms (d1-d3)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly solublePBS (pH 7.2): Slightly soluble
SMILES
[15NH2][C@](C([2H])([2H])S)([2H])C(O)=O
InChi Code
InChI=1S/C3H7NO2S/c4-2(1-7)3(5)6/h2,7H,1,4H2,(H,5,6)/t2-/m0/s1/i1D2,2D,4+1
InChi Key
XUJNEKJLAYXESH-KIYJLCFFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $448

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    5 mg

    $2,016

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    Cayman Chemical
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    Product Description

    L-Cysteine-15N-d3 is intended for use as an internal standard for the quantification of L-cysteine (Item No. 33309) by GC- or LC-MS. L-Cysteine is a conditionally essential amino acid.1,2 It is produced from L-methionine through the transsulfuration pathway.1 L-Cysteine can also be derived from dietary sources and protein turnover. It is a precursor in the biosynthesis of the intracellular antioxidant glutathione (GSH; Item No. 10007461). L-Cysteine supplementation increases GSH levels as well as decreases oxidative stress and pro-inflammatory cytokine levels in various rat and porcine disease models, including type 2 diabetes, aging, and inflammatory bowel disease (IBD). It is also an excitotoxin, inducing neuronal damage by overactivation of NMDA receptors.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yin, J., Ren, W., Yang, G., et al. L-Cysteine metabolism and its nutritional implications. Mol. Nutr. Food Res. 60(1), 134-146 (2016).

    2. Janáky, R., Varga, V., Hermann, A., et al. Mechanisms of L-cysteine neurotoxicity. Neurochem. Res. 25(9-10), 1397-1405 (2000).