A metabolite of glimepiride
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Parent Compound(s)
12090Glimepiride
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trans-carboxy Glimepiride

Item No. 34277

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
trans-4-[[[[[4-[2-[[(3-ethyl-2,5-dihydro-4-methyl-2-oxo-1H-pyrrol-1-yl)carbonyl]amino]ethyl]phenyl]sulfonyl]amino]carbonyl]amino]-cyclohexanecarboxylic acid
CAS Number
1217739-04-2
Molecular Formula
C24H32N4O7S
Formula Weight
520.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: slightly solubleEthyl Acetate: heated, sonicated
SMILES
O=C(NS(=O)(C1=CC=C(CCNC(N2C(C(CC)=C(C2)C)=O)=O)C=C1)=O)N[C@H]3CC[C@@H](CC3)C(O)=O
InChi Code
InChI=1S/C24H32N4O7S/c1-3-20-15(2)14-28(21(20)29)24(33)25-13-12-16-4-10-19(11-5-16)36(34,35)27-23(32)26-18-8-6-17(7-9-18)22(30)31/h4-5,10-11,17-18H,3,6-9,12-14H2,1-2H3,(H,25,33)(H,30,31)(H2,26,27,32)/t17-,18-
InChi Key
MMZLACCSCMGVHL-IYARVYRRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $325

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    Product Description

    trans-carboxy Glimepiride is a metabolite of the sulfonylurea glimepiride (Item No. 12090).1 It is formed from glimepiride in a two-step process mediated by the cytochrome P450 (CYP) isoform CYP2C9 and cytosolic enzymes.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Noh, K., Kim, E., Jeong, T.C., et al. Simultaneous determination of glimepiride and its metabolites in human plasma by liquid chromatography coupled to a tandem mass spectrometry. Arch. Pharm. Res. 34(12), 2073-2078 (2011).