An active metabolite of glimepiride
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Parent Compound(s)
12090Glimepiride
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trans-hydroxy Glimepiride

Item No. 34278

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-ethyl-2,5-dihydro-N-[2-[4-[[[[[trans-4-(hydroxymethyl)cyclohexyl]amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-4-methyl-2-oxo-1H-pyrrole-1-carboxamide
CAS Number
600177-94-4
Molecular Formula
C24H34N4O6S
Formula Weight
506.6
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: very slightly solubleMethanol: slightly soluble
SMILES
O=C(NS(=O)(C1=CC=C(CCNC(N2C(C(CC)=C(C2)C)=O)=O)C=C1)=O)N[C@@H]3CC[C@H](CC3)CO
InChi Code
InChI=1S/C24H34N4O6S/c1-3-21-16(2)14-28(22(21)30)24(32)25-13-12-17-6-10-20(11-7-17)35(33,34)27-23(31)26-19-8-4-18(15-29)5-9-19/h6-7,10-11,18-19,29H,3-5,8-9,12-15H2,1-2H3,(H,25,32)(H2,26,27,31)/t18-,19-
InChi Key
YUNQMQLWOOVHKI-WGSAOQKQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $362

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    Cayman Chemical
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    OBESITY RESEARCH SOLUTIONS
    Product Description

    trans-hydroxy Glimepiride is an active metabolite of the sulfonylurea glimepiride (Item No. 12090).1 It is formed from glimepiride primarily in the liver by the cytochrome P450 (CYP) isoform CYP2C9.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Langtry, H.D., and Balfour, J.A. Glimepiride. A review of its use in the management of type 2 diabetes mellitus. Drugs 55(4), 563-584 (1998).