A saponin and metabolite of ginsenoside Rc
Related Products
Isomer(s)
29705Gypenoside IX 24976Notoginsenoside Ft1
Parent Compound(s)
29088Ginsenoside Rc
Technical Support & Resources

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Product Categories

Product Type

Biochemicals
Natural Products
Saponins

Research Area

Cancer
Cell Death

Notoginsenoside Fe

Item No. 34297

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3β,12β)-3-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-20-yl 6-O-α-L-arabinofuranosyl-β-D-glucopyranoside
CAS Number
88105-29-7
Synonyms
  • Ginsenoside Fe
  • Ginsenoside Mb
Molecular Formula
C47H80O17
Formula Weight
917.1
Purity
≥90%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 5 mg/mlEthanol: 1 mg/ml
SMILES
C[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@@H]5O[C@H]([C@@H]([C@H]5O)O)CO)C)O)([H])[C@@]6([C@@](C(C)([C@H](CC6)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)C)([H])CC1)CC[C@]12[C@@](C[C@H]([C@@]3([H])[C@]2(CC[C@]3([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@@H]5O[C@H]([C@@H]([C@H]5O)O)CO)C)O)([H])[C@@]6([C@@](C(C)([C@H](CC6)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)C)([H])CC1)C
InChi Code
InChI=1S/C47H80O17/c1-22(2)10-9-14-47(8,64-42-39(58)36(55)34(53)27(62-42)21-59-40-37(56)33(52)26(20-49)60-40)23-11-16-46(7)31(23)24(50)18-29-44(5)15-13-30(43(3,4)28(44)12-17-45(29,46)6)63-41-38(57)35(54)32(51)25(19-48)61-41/h10,23-42,48-58H,9,11-21H2,1-8H3/t23-,24+,25+,26-,27+,28-,29+,30-,31-,32+,33-,34+,35-,36-,37+,38+,39+,40+,41-,42-,44-,45+,46+,47-/m0/s1
InChi Key
MYBAONSAUGZRAX-UBQYYSLZSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    25 mg

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    Product Description

    Notoginsenoside Fe is a saponin and metabolite of ginsenoside Rc (Item No. 29088) that has been found in P. notoginseng.1,2 It is cytotoxic to L1210 murine skin lymphocytic leukemia cells (IC50 = 80 µM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bae, E.-A., Choo, M.-K., Park, E.-K., et al. Metabolism of ginsenoside Rc by human intestinal bacteria and its related antiallergic activity. Biol. Pharm. Bull. 25(6), 743-747 (2002).

    2. Liu, F., Ma, N., Xia, F.-B., et al. Preparative separation of minor saponins from Panax notoginseng leaves using biotransformation, macroporous resins, and preparative high-performance liquid chromatography. J. Ginseng Res. 43(1), 105-115 (2019).