A flavonoid with antioxidant and anticancer activities
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Isomer(s)
10006084Hesperetin
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Blumeatin

Item No. 34809

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2S-(3,5-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-7-methoxy-4H-1-benzopyran-4-one
CAS Number
118024-26-3
Molecular Formula
C16H14O6
Formula Weight
302.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: soluble
λmax
288 nm
SMILES
OC1=C2C(O[C@@H](CC2=O)C3=CC(O)=CC(O)=C3)=CC(OC)=C1
InChi Code
InChI=1S/C16H14O6/c1-21-11-5-12(19)16-13(20)7-14(22-15(16)6-11)8-2-9(17)4-10(18)3-8/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1
InChi Key
YEYLMQKEGSQNGZ-AWEZNQCLSA-N
Origin
Plant/Blumea balsamifera
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $57

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    5 mg

    $209

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    10 mg

    $363

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    25 mg

    $834

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    Cayman Chemical
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    Product Description

    Blumeatin is a flavonoid that has been found in Blumea and has antioxidant and anticancer activities.1,2,3 It scavenges DPPH (Item No. 14805) radicals in a cell-free assay with a 50% scavenging capacity (SC50) value of 90.8 µg/ml.1 Blumeatin (10 and 100 µM) decreases carbon tetrachloride-induced lipid peroxidation in isolated rhesus monkey hepatocytes.2 It is also cytotoxic to KB oral carcinoma cells (IC50 = 47.72 µg/ml).3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nessa, F., Ismail, Z., Mohamed, N., et al. Free radical-scavenging activity of organic extracts and of pure flavonoids of Blumea balsamifera DC leaves. Food Chem. 88(2), 243-252 (2004).

    2. Zhao, J.H., Xu, S.-B., Wang, Z.-L., et al. Protective actions of blumea flavanones on primary cultured hepatocytes and liver subcellular organelle against lipid peroxidation. J. Chin. Pharma. Sci. 7(3), 152-156 (1998).

    3. Saewan, N., Koysomboon, S., and Chantrapromma, K. Anti-tyrosinase and anti-cancer activities of flavonoids from Blumea balsamifera DC. J. Med. Plant Res. 5(6), 1018-1025 (2011).