An Analytical Reference Standard
Features
  • This product has been formulated as an exempt preparation which meets criteria established by the US DEA
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for academic research at qualified institutions; please contact our sales department for pricing
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Protonitazene (hydrochloride) (exempt preparation)

Item No. 38143

Exempt Product (US)
Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Pronitazene
Technical Information
Formal Name
N,N-diethyl-5-nitro-2-[(4-propoxyphenyl)methyl]-1H-benzimidazole-1-ethanamine, monohydrochloride
CAS Number
119276-01-6
Molecular Formula
C23H30N4O3 • HCl
Formula Weight
447.0
Purity
≥98%
Formulation
A 1 mg/ml solution in methanol
λmax
240, 302 nm
SMILES
CCN(CC)CCN1C(CC2=CC=C(OCCC)C=C2)=NC3=CC([N+]([O-])=O)=CC=C31.Cl
InChi Code
InChI=1S/C23H30N4O3.ClH/c1-4-15-30-20-10-7-18(8-11-20)16-23-24-21-17-19(27(28)29)9-12-22(21)26(23)14-13-25(5-2)6-3;/h7-12,17H,4-6,13-16H2,1-3H3;1H
InChi Key
HXFAZCCRNXARMH-UHFFFAOYSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $143

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    Product Description

    Protonitazene (hydrochloride) (exempt preparation) (Item No. 38143) is an analytical reference standard categorized as an opioid.1 Protonitazene has analgesic effects in mice.2 Protonitazene is regulated as a Schedule I compound in the United States. Protonitazene (hydrochloride) (exempt preparation) (Item No. 38143) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vandeputte, M.M., Van Uytfanghe, K., Layle, N.K., et al. Synthesis, chemical characterization, and µ-opioid receptor activity assessment of the emerging group of "nitazene" 2-benzylbenzimidazole synthetic opioids. ACS Chem. Neurosci. 12(7), 1241-1251 (2021).

    2. Ujváry, I., Christie, R., Evans-Brown, M., et al. DARK classics in chemical neuroscience: Etonitazene and related benzimidazoles. ACS Chem. Neurosci. 12(7), 1072-1092 (2021).

    Product Citations

    Sapkota, R., Lomnicki, E.E., and Subedi, B. Nitazenes discharged during Super Bowl and Mardi Gras celebrations in New Orleans, USA. Environ. Sci. Tech. Lett. (2026).

    Leonard, A.C., Lenert-Mondou, C., Chayer, R., et al. Computational design of dynamic biosensors for emerging synthetic opioids. BioRxiv (2025).