An mRNA for the expression of mCherry
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Product Type

Lipid Nanoparticles (LNPs)
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mCherry mRNA (Cap-1; 5mCTP; ψUTP)

Item No. 39799

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Emission
610 nm
Excitation
587 nm
Amino Acids
336 translated (996 nucleotides)
Formulation
1 mM sodium citrate, pH 6.4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    100 µg

    $303

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    $1,513

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    Product Description

    mCherry mRNA (Cap-1; 5mCTP; ψUTP) encodes mCherry, a red fluorescent protein and derivative of Discosoma red fluorescent protein (DsRed) that displays excitation and emission maxima of 587 and 610 nm, respectively.1 It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap-1 structure with high capping efficiency. mCherry mRNA is also polyadenylated and modified with 5-methylcytidine-5'-triphosphate (5mCTP) and ψUTP to reduce the host cell immune response and enhance mRNA stability. Encapsulation of mCherry mRNA (Cap-1; 5mCTP; ψUTP) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of mCherry fluorescent protein in vitro or in vivo.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shaner, N.C., Campbell, R.E., Steinbach, P.A., et al. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22(12), 1567-1572 (2004).

    2. Skelton, R., Roach, A.H., Prudhomme, L.E., et al. Formulation of lipid-free polymeric mesoscale nanoparticles encapsulating mRNA. Pharm. Res. 39(11), 2699-2707 (2022).