An antiviral nucleoside derivative
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2'-Fluoro-2'-deoxy-arabino-Uridine

Item No. 40303

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione
CAS Number
69123-94-0
Synonyms
  • 2′-Arafluoro-2′-deoxyuridine
Molecular Formula
C9H11FN2O5
Formula Weight
246.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
F[C@@H]1[C@H](N2C(NC(C=C2)=O)=O)O[C@@H]([C@H]1O)CO
InChi Code
InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6+,7-,8-/m1/s1
InChi Key
UIYWFOZZIZEEKJ-PXBUCIJWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $186

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    1 g

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    5 g

    $838

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    Cayman Chemical
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    Product Description

    2'-Fluoro-2'-deoxy-arabino-uridine is an antiviral nucleoside and a derivative of the pyrimidine nucleoside uridine (Item No. 20300).1 It inhibits the replication of herpes simplex virus 1 (HSV-1) in infected Vero cells when used at a concentration of 1 µg/ml and does not induce cytotoxicity in L5178Y or P815 cells (IC50 = >10 µg/ml for both).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Watanabe, K.A., Reichman, U., Hirota, K., et al. Nucleosides. 110. Synthesis and antiherpes virus activity of some 2'-fluoro-2'-deoxyarabinofuranosylpyrimidine nucleosides. J. Med. Chem. 22(1), 21-24 (1979).