A glycerophospholipid
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Phosphatidylethanolamine (E. coli)

Item No. 45090

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
CAS Number
94581-14-3
Synonyms
  • Cephalin
  • PE (E. coli)
Purity
≥95% (mixture)
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly soluble: 0.1-1 mg/ml
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $79

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    5 mg

    $257

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    10 mg

    $435

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    Cayman Chemical
    Learn More About Leveraging Helper Lipids to Achieve Versatile LNPs
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    Product Description

    Phosphatidylethanolamine is the most abundant phospholipid in prokaryotes and the second most abundant found in the membrane of mammalian, plant, and yeast cells, comprising approximately 75 and 25% of total phospholipids in E. coli and mammals, respectively.1,2 In E. coli, it is synthesized mainly through the decarboxylation of phosphatidylserine that is formed from cytidine diphosphate-diglycerides and L-serine.3 Phosphatidylethanolamine deficiency in E. coli prevents proper assembly of lactose permease, suggesting a role as a lipid chaperone.4 This product contains phosphatidylethanolamine molecular species with primarily C18:1, C16:0, and C17:0 fatty acyl chains.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vance, J.E., and Tasseva, G. Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells. Biochim. Biophys. Acta 1831(3), 543-554 (2013).

    2. Raetz, C.R.H., and Dowhan, W. Biosynthesis and function of phospholipids in Escherichia coli. The Journal of Biological Chemisty 265(3), 1235-1238 (1990).

    3. Kanfer, J.N., and Kennedy, E.P. Metabolism and function of bacterial lipids. The Journal of Biological Chemisty 238, 2919-2922 (1964).

    4. Bogdanov, M., Sun, J., Kaback, H.R., et al. A phospholipid acts as a chaperone in assembly of a membrane transport protein. The Journal of Biological Chemisty 271(20), 11615-11618 (1996).