An Analytical Reference Material
Features
  • This product is qualified as a Reference Material that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This product is intended to be used as an analytical reference standard
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Fentanyl-d5 (hydrochloride)

Item No. 14721

Restricted Product (Schedule II)
Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-phenyl-d5-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide, monohydrochloride
CAS Number
2747915-16-6
Molecular Formula
C22H23D5N2O • HCl
Formula Weight
378.0
Purity
≥98%
Formulation
A neat solid
SMILES
O=C(N(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C2CCN(CCC3=CC=CC=C3)CC2)CC.Cl
InChi Code
InChI=1S/C22H28N2O.ClH/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19;/h3-12,21H,2,13-18H2,1H3;1H/i4D,7D,8D,11D,12D;
InChi Key
LHCBOXPPRUIAQT-QGDUSKDSSA-N
Regulatory Information
DEA Schedule
II
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Fentanyl-d5 (hydrochloride) is an analytical reference material intended for use as an internal standard for the quantification of fentanyl (Item Nos. 23580 | 14719 | 22659 | ISO60197) by GC- or LC-MS. Fentanyl is categorized as an opioid.1,2 It is more effective than morphine (Item No. ISO60147) at reducing pain but is also more lethal.3 Fentanyl is highly abused and is associated with many fatal overdoses.4 Fentanyl-d5 (hydrochloride) is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Burns, S.M., Cunningham, C.W., and Mercer, S.L. DARK classics in chemical neuroscience: Fentanyl. ACS Chem. Neurosci. 9(10), 2428-2437 (2018).

    2. Raynor, K., Kong, H., Chen, Y., et al. Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors. Mol. Pharm. 45(2), 330-334 (1994).

    3. Higashikawa, Y., and Suzuki, S. Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues. Forensic Toxicol. 26(1), 1-5 (2008).

    4. Armenian, P., Vo, K.T., Barr-Walker, J., et al. Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review. Neuropharmacology 134(Pt A), 121-132 (2018).

    Product Citations

    Hassanien, S.H., Bassman, J.R., Perrien Naccarato, C.M., et al. In vitro pharmacology of fentanyl analogs at the human mu opioid receptor and their spectroscopic analysis. Drug Test. Anal. 12(8), 1212-1221 (2020).