A Certified Reference Material
Features
  • This product is qualified as a Certified Reference Material (CRM) that has been manufactured and tested to meet ISO/IEC 17025 and ISO 17034 international standards
  • This CRM has been characterized by metrologically valid procedures and may be used as a quantitative analytical reference standard
  • Certificate of analysis provides the certified property values and the associated uncertainties, including a statement of metrological traceability for the certified values
  • Possession of a DEA Controlled Substance registration is not necessary nor is a DEA 222 form required to purchase this product
  • Bulk material is available for qualified institutions; please contact our sales department for pricing
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Fentanyl-d5 (hydrochloride) (CRM)

A 100 µg/ml solution in methanol

Item No. 19928

Exempt Product (US)
Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-phenyl-d5-N-[1-(2-phenylethyl)-4-piperidinyl]-propanamide, monohydrochloride
CAS Number
2747915-16-6
Molecular Formula
C22H23D5N2O • HCl
Formula Weight
378.0
Formulation
A 100 µg/ml solution in methanol
SMILES
O=C(N(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])C2CCN(CCC3=CC=CC=C3)CC2)CC.Cl
InChi Code
InChI=1S/C22H28N2O.ClH/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19;/h3-12,21H,2,13-18H2,1H3;1H/i4D,7D,8D,11D,12D;
InChi Key
LHCBOXPPRUIAQT-QGDUSKDSSA-N
Regulatory Information
DEA Exempt Notification
This product is a DEA exempt preparation of a scheduled compound - does not require DEA Controlled Substance registration or DEA 222 form. For alternate sizes please contact sales.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    100 µg

    $38

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    Product Description

    Fentanyl-d5 (hydrochloride) (CRM) (Item No. 19928) is a certified reference material intended for use as an internal standard for the quantification of fentanyl (Item Nos. 23580 | 14719 | 22659 | ISO60197) by GC- or LC-MS. Fentanyl is categorized as an opioid.1,2 It is more effective than morphine (Item No. ISO60147) at reducing pain but is also more lethal.3 Fentanyl is highly abused and is associated with many fatal overdoses.4 Fentanyl is regulated as a Schedule II compound in the United States. Fentanyl-d5 (hydrochloride) (CRM) (Item No. 19928) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Burns, S.M., Cunningham, C.W., and Mercer, S.L. DARK classics in chemical neuroscience: Fentanyl. ACS Chem. Neurosci. 9(10), 2428-2437 (2018).

    2. Raynor, K., Kong, H., Chen, Y., et al. Pharmacological characterization of the cloned κ-, δ-, and μ-opioid receptors. Mol. Pharm. 45(2), 330-334 (1994).

    3. Higashikawa, Y., and Suzuki, S. Studies on 1-(2-phenethyl)-4-(N-propionylanilino)piperidine (fentanyl) and its related compounds. VI. Structure-analgesic activity relationship for fentanyl, methyl-substituted fentanyls and other analogues. Forensic Toxicol. 26(1), 1-5 (2008).

    4. Armenian, P., Vo, K.T., Barr-Walker, J., et al. Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review. Neuropharmacology 134(Pt A), 121-132 (2018).

    Product Citations

    Hassanien, S.H., Bassman, J.R., Perrien Naccarato, C.M., et al. In vitro pharmacology of fentanyl analogs at the human mu opioid receptor and their spectroscopic analysis. Drug Test. Anal. 12(8), 1212-1221 (2020).