Deoxycholic Acid (CAS 83-44-3) | Cayman Chemical
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Deoxycholic Acid

Item № 20756
CAS № 83-44-3
Purity ≥95%
product image
                (CAS 83-44-3)
SIZE PRICE QUANTITY SUBTOTAL
CART TOTAL
     5 g $10.00 0.00
     10 g $19.00 0.00
     50 g $35.00 0.00
     100 g $50.00 0.00

Pricing updated 2018-07-16. Prices are subject to change without notice.

Description
Synonyms
  • Cholanoic Acid
  • DCA
  • NSC 8797

Deoxycholic acid (DCA) is a secondary bile acid produced from cholic acid (Item No. 20250) by bacterial action in the colon.1 It is usually conjugated with glycine or taurine and acts as a detergent in the emulsification of fats for intestinal absorption.2,3 Elevated levels of DCA are strongly associated with the development of colon cancer.4

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Technical Information
Formal Name
(3α,5β,12α)-3,12-dihydroxy-cholan-24-oic acid
CAS Number
83-44-3
Synonyms
  • Cholanoic Acid
  • DCA
  • NSC 8797
Molecular Formula
C24H40O4
Formula Weight
392.6
Purity
≥95%
Formulation
A crystalline solid
SMILES
O[C@@H]1CC[C@@]2(C)[C@@](CC[C@]3([H])[C@]2([H])C[C@H](O)[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCC(O)=O)([H])C1
InChI Code
InChI=1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1
InChI Key
KXGVEGMKQFWNSR-LLQZFEROSA-N

Warning - this product is not for human or veterinary use.

Shipping & Storage
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
Stability
≥ 2 years
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Additional Information

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References & Product Citations
Product Description References

1. Huang, J., Bathena, S.P.R., Csanaky, I., et al. Simultaneous characterization of bile acids and their sulfate metabolites in mouse liver, plasma, bile, and urine using LC-MS/MS. Journal of Pharmaceutical & Biomedical Analysis 55(5), 1111-1119 (2011).

2. Zhang, Y., and Klaassen, C.D. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice. Journal of Lipid Research 51(11), 3230-3242 (2010).

3. Semba, R.D., Gonzalez-Freier, M., Moaddel, R., et al. Environmental enteric dysfunction is associated with altered bile acid metabolism. J.Pediatr.Gastenterol.Nutr. (2016).

4. Centuori, S.M., and Martinez, J.D. Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancer. Dig. Dis. Sci. 59(10), 2367-2380 (2014).

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