Pricing updated 2018-07-16. Prices are subject to change without notice.
Deoxycholic acid (DCA) is a secondary bile acid produced from cholic acid (Item No. 20250) by bacterial action in the colon.1 It is usually conjugated with glycine or taurine and acts as a detergent in the emulsification of fats for intestinal absorption.2,3 Elevated levels of DCA are strongly associated with the development of colon cancer.4
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Huang, J., Bathena, S.P.R., Csanaky, I., et al. Simultaneous characterization of bile acids and their sulfate metabolites in mouse liver, plasma, bile, and urine using LC-
2. Zhang, Y., and Klaassen, C.D. Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice. Journal of Lipid Research 51(11), 3230-3242 (2010).
Semba, R.D., Gonzalez-
Centuori, S.M., and Martinez, J.D. Differential regulation of EGFR-