An internal standard for the quantification of medetomidine
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Unlabeled Version(s)
16454Medetomidine (hydrochloride)
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Medetomidine-13C-d3 (hydrochloride)

Item No. 25041

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(1-(2,3-dimethylphenyl)ethyl-2-13C-2,2,2-d3)-1H-imidazole, monohydrochloride
CAS Number
1216630-06-6
Synonyms
  • MVP 785-13C-d3
Molecular Formula
C12[13C]H13D3N2 • HCl
Formula Weight
240.8
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Slightly soluble
SMILES
CC1=C(C)C(C([13C]([2H])([2H])[2H])C2=CN=CN2)=CC=C1.Cl
InChi Code
InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/i3+1D3;
InChi Key
VPNGEIHDPSLNMU-RWALGPICSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $309

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    Product Description

    Medetomidine-13C-d3 is intended for use as an internal standard for the quantification of medetomidine (Item No. 16454) by GC- or LC-MS. Medetomidine is an agonist of α2-adrenergic receptors (α2-ARs; Ki = 1.08 nM).1 It is selective for α2-ARs over α1-ARs (Ki = 1,750 nM). Medetomidine induces sedation in dogs.2 Formulations containing medetomidine have been used as sedatives in veterinary medicine.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Virtanen, R., Savola, J.M., Saano, V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist. Eur. J. Pharmacol. 150(1-2), 9-14 (1988).

    2. Vainio, O., and Vähä-Vahe, T. Reversal of medetomidine sedation by atipamezole in dogs. J. Vet. Pharmacol. Ther. 13(1), 15-22 (1990).