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Medetomidine-d3 (hydrochloride)

Item No. 41734

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • MPV 785-d3
Technical Information
Formal Name
5-[1-(2,3-dimethylphenyl)ethyl-2,2,2-d3]-1H-imidazole, monohydrochloride
CAS Number
1246820-20-1
Molecular Formula
C13H13D3N2 • HCl
Formula Weight
239.8
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly Soluble: 1-10 mg/mlEthanol: Sparingly Soluble: 1-10 mg/ml
SMILES
CC1=C(C)C(C(C([2H])([2H])[2H])C2=CN=CN2)=CC=C1.Cl
InChi Code
InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/i3D3;
InChi Key
VPNGEIHDPSLNMU-FJCVKDQNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Medetomidine-d3 (hydrochloride) (Item No. 41734) is intended for use as an internal standard for the quantification of medetomidine (Item Nos. 38807 | 38582) by GC- or LC-MS. Medetomidine is categorized as a sedative.1 It induces sedation in dogs. Medetomidine has analgesic activity alone and an additive analgesic effect in combination with fentanyl (Item Nos. ISO60197 | 14719 | 23580) or morphine (Item Nos. ISO60147 | 15464) in rats.2 It has been found in fentanyl samples seized by law enforcement.3 Formulations containing medetomidine have been used as veterinary sedatives. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vainio, O., and Vähä-Vahe, T. Reversal of medetomidine sedation by atipamezole in dogs. J. Vet. Pharmacol. Ther. 13(1), 15-22 (1990).

    2. Ossipov, M.H., Harris, S., Lloyd, P., et al. Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergy. Anesthesiology 73(6), 1227-1235 (1990).

    3. Sisco, E., and Appley, M. Identification of the veterinary sedative medetomidine in combination with opioids and xylazine in Maryland. J. Forensic Sci. (2023).