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Medetomidine (hydrochloride)

Item No. 38582

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • MPV 785
Technical Information
Formal Name
5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole, monohydrochloride
CAS Number
86347-15-1
Molecular Formula
C13H16N2 • HCl
Formula Weight
236.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
SMILES
CC1=C(C)C(C(C)C2=CN=CN2)=CC=C1.Cl
InChi Code
InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H
InChi Key
VPNGEIHDPSLNMU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Medetomidine (hydrochloride) (Item No. 38582) is an analytical reference standard categorized as a sedative.1 Medetomidine induces sedation in dogs. It has analgesic activity alone and an additive analgesic effect in combination with fentanyl (Item Nos. ISO60197 | 14719 | 23580) or morphine (Item Nos. ISO60147 | 15464) in rats.2 Medetomidine has been found in fentanyl samples seized by law enforcement.3 Formulations containing medetomidine have been used as veterinary sedatives. This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 16454).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Vainio, O., and Vähä-Vahe, T. Reversal of medetomidine sedation by atipamezole in dogs. J. Vet. Pharmacol. Ther. 13(1), 15-22 (1990).

    2. Ossipov, M.H., Harris, S., Lloyd, P., et al. Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergy. Anesthesiology 73(6), 1227-1235 (1990).

    3. Sisco, E., and Appley, M. Identification of the veterinary sedative medetomidine in combination with opioids and xylazine in Maryland. J. Forensic Sci. (2023).

    Product Citations

     Medetomidine. NPS Discovery—New Drug Monograph (2023).