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Item No. 38807

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REQUEST YOURSMedetomidine (hydrochloride) (CRM) (Item No. 38807) is a certified reference material categorized as a sedative.1 Medetomidine induces sedation in dogs. It has analgesic activity alone, and an additive analgesic effect in combination with fentanyl (Item Nos. ISO60197 | 14719 | 23580) or morphine (Item Nos. ISO60147 | 15464), in rats.2 Medetomidine has been found in fentanyl samples seized by law enforcement.3 Formulations containing medetomidine have been used as veterinary sedatives. This product is intended for analytical forensic applications. This product is also available as a general research tool (Item No. 16454).
WARNING This product is not for human or veterinary use.
1. Reversal of medetomidine sedation by atipamezole in dogs. J. Vet. Pharmacol. Ther. 13(1), 15-22 (1990).
2. Antinociceptive interaction between opioids and medetomidine: Systemic additivity and spinal synergy. Anesthesiology 73(6), 1227-1235 (1990).
3. Identification of the veterinary sedative medetomidine in combination with opioids and xylazine in Maryland. J. Forensic Sci. (2023).