A prodrug form of fluphenazine
Related Products
Active Metabolite(s)
23555Fluphenazine (hydrochloride)
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Fluphenazine decanoate

Item No. 39903

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
decanoic acid, 2-[4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazinyl]ethyl ester
CAS Number
5002-47-1
Synonyms
  • NSC 169510
  • QD-10733
  • SQ 10,733
Molecular Formula
C32H44F3N3O2S
Formula Weight
591.8
Purity
≥95%
Formulation
A solution in ethanol
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
O=C(CCCCCCCCC)OCCN1CCN(CCCN2C3=C(SC4=CC=C(C(F)(F)F)C=C42)C=CC=C3)CC1
InChi Code
InChI=1S/C32H44F3N3O2S/c1-2-3-4-5-6-7-8-14-31(39)40-24-23-37-21-19-36(20-22-37)17-11-18-38-27-12-9-10-13-29(27)41-30-16-15-26(25-28(30)38)32(33,34)35/h9-10,12-13,15-16,25H,2-8,11,14,17-24H2,1H3
InChi Key
VIQCGTZFEYDQMR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    10 mg

    $32

    Add

    50 mg

    $136

    Add

    100 mg

    $240

    Add

    500 mg

    $1,117

    Add
    Product Description

    Fluphenazine decanoate is a prodrug form of the dopamine D1 and D2 receptor antagonist fluphenazine (Item No. 23555).1 It induces random mouth movements in rats, an effect that can be reversed by the dopamine receptor antagonists raclopride (Item No. 17422) or SCH 23390 (Item No. 15631). Chronic administration of fluphenazine decanoate (3 mg/kg per day) increases serum levels of prolactin and decreases luteinizing hormone (LH) and follicle stimulating hormone (FSH), as well as decreases desire to mate and litter size, in male rats.2 It increases lethargy and passive contact and reduces self-grooming, social grooming, auditory startle response, and propensity to attack other animals in monkeys when chronically administered.3 Formulations containing fluphenazine decanoate have been used in the treatment of chronic schizophrenia.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Stoessl, A.J., Dourish, C.T., and Iversen, S.D. Chronic neuroleptic-induced mouth movements in the rat: Suppression by CCK and selective dopamine D1 and D2 receptor antagonist. Psychopharmacology (Berl.) 98(3), 372-379 (1989).

    2. Gill-Sharma, M.K., Aleem, M., Sethi, G., et al. Antifertility effects of fluphenazine in adult male rats. J. Endocrinol. Invest. 26(4), 316-326 (2003).

    3. O'Keeffe, R.T., and Lifshitz, K. Nonhuman primates in neurotoxicity screening and neurobehavioral toxicity studies. J. Am. Coll. Toxicol. 8(1), 127-140 (1989).