A terpenoid with diverse biological activities
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α-Terpinene

Item No. 23178

Technical Information
Formal Name
1-methyl-4-(1-methylethyl)-1,3-cyclohexadiene
CAS Number
99-86-5
Synonyms
  • p-Mentha-1,3-diene
Molecular Formula
C10H16
Formula Weight
Purity
≥95%
A liquid
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
213, 266 nm
SMILES
CC1=CC=C(C(C)C)CC1
InChi Code
InChI=1S/C10H16/c1-8(2)10-6-4-9(3)5-7-10/h4,6,8H,5,7H2,1-3H3
InChi Key
YHQGMYUVUMAZJR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    α-Terpinene is a terpenoid that has been found in Cannabis and has diverse biological activities, including acaricidal, antiprotozoal, and antioxidant properties.1,2 α-Terpinene induces 99 and 46% mortality of male and female T. putrescentiae larvae, respectively, when administered at a dose of 32.3 µl/L via inhalation.3 In mice infected with T. evansi, it increases longevity when used alone and decreases mortality when used in combination with diminazene aceturate (Item No. 18678).4 It also scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals when used at a concentration of 10 mM.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Giese, M.W., Lewis, M.A., Giese, L., et alDevelopment and Validation of a Reliable and Robust Method for the Analysis of Cannabinoids and Terpenes in Cannabis. J. AOAC Int. 98(6), 1503-1522 (2015).

    2. Ross, S.A., and ElSohly, M.A. The volatile oil composition of fresh and air-dried buds of Cannabis sativa. J. Nat. Prod. 59(1), 49-51 (1996).

    3. Sánchez-Ramos, I., and Castañera, P. Acaricidal activity of natural monoterpenes on Tyrophagus putrescentiae (Schrank), a mite of stored food. J. Stored Prod. Res. 37(1), 93-101 (2000).

    4. Baldissera, M.D., Grando, T.H., Souza, C.F., et alIn vitro and in vivo action of terpinen-4-ol, γ-terpinene, and α-terpinene against Trypanosoma evansi. Exp. Parasitol. 162, 43-48 (2016).

    5. Kim, H.J., Chen, F., Wu, C., et alEvaluation of antioxidant activity of Australian tea tree (Melaleuca alternifolia) oil and its components. J. Agric. Food Chem. 52(10), 2849-2854 (2004).