A polyphenol with antioxidant and antiviral activities
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Methyl 3,4-Dihydroxyphenylacetate

Item No. 30637

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3,4-dihydroxy-benzeneacetic acid, methyl ester
CAS Number
25379-88-8
Synonyms
  • Methyl 2-(3,4-dihydroxyphenyl)acetate
  • 3,4-Dihydroxyphenylacetic acid methyl ester
Molecular Formula
C9H10O4
Formula Weight
182.2
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMF: 30mg/mLDMSO: 30mg/mLEthanol: 30mg/mLPBS (pH 7.2): 10mg/mL
SMILES
OC1=C(O)C=C(CC(OC)=O)C=C1
InChi Code
InChI=1S/C9H10O4/c1-13-9(12)5-6-2-3-7(10)8(11)4-6/h2-4,10-11H,5H2,1H3
InChi Key
UGFILLIGHGZLHE-UHFFFAOYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    250 mg

    $103

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    500 mg

    $153

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    1 g

    $283

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    Cayman Chemical
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    Product Description

    Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found in I. aquifolium seeds and has antioxidant and antiviral activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 0.0025 mg/ml).1 Methyl 3,4-dihydroxyphenylacetate (0.01 µg/ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nahar, L., Russell, W.R., Middleton, M., et al. Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifolium. Acta Pharm. 55(2), 187-193 (2005).

    2. Wang, L., Wang, J., Wang, L., et al. Anti-enterovirus 71 agents of natural products. Molecules 20(9), 16320-16333 (2015).