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Lipid Nanoparticle Formulation:
Basic Concepts & Preparation Procedures

  • Types of LBDD Systems
  • Structural Components & Cargo
  • Design & Procedures
  • Stability & Storage
  • Characterization & Assessment
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Cayman Co-authored Publications

Liao, P., Wang, W., Wang, W., et alCD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4. Cancer Cell 40(4), 365-378 (2022).

Gambini, L., Udompholkul, P., Baggio, C., et alDesign, synthesis, and structural characterization of lysine covalent BH3 peptides targeting Mcl-1. J. Med. Chem. 64(8), 4903-4912 (2021).

Wang, W., Green, M., Choi, J.E., et alCD8+ T cells regulate tumour ferroptosis during cancer immunotherapy. Nature 569(7755), 270-274 (2019).

Wagner, F.F., Benajiba, L., Campbell, A.J., et alExploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci. Transl. Med. 10(431), eaam8460 (2018).

Stein, A.J., Bain, G., Prodanovich, P., et alStructural basis for inhibition of human autotaxin by four potent compounds with distinct modes of binding. Mol. Pharmacol. 88(6), 982-992 (2015).