An mRNA for the expression of tdTomato
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Product Categories

Product Type

Lipid Nanoparticles (LNPs)
Cargos

Application

Fluorescence

tdTomato mRNA (Cap-1; m1Ψ)

Item No. 43681

Product Insert (PDF)
Technical Information
Synonyms
  • tdTomato mRNA (Cap-1; N1-Methylpseudouridine)
Emission
581 nm
Excitation
554 nm
Formulation
1 mM Sodium citrate, pH 6.4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    100 µg

    $504

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    1 mg

    $1,764

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    Cayman Chemical
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    Product Description

    tdTomato mRNA (Cap-1; m1Ψ) encodes for tdTomato, a red fluorescent protein and derivative of Discosoma red fluorescent protein (DsRed) that displays excitation and emission maxima of 554 and 581 nm, respectively.1 It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap-1 structure with high capping efficiency. tdTomato mRNA is also polyadenylated and modified with N1-methylpseudouridine (m1Ψ) to reduce the host cell immune response and enhance mRNA stability. Encapsulation of tdTomato mRNA (Cap-1; m1Ψ) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of tdTomato.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Shaner, N.C., Campbell, R.E., Steinbach, P.A., et al. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat. Biotechnol. 22(12), 1567-1572 (2004).