An mRNA for the expression of ER-mScarlet
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ER-mScarlet Probe mRNA (Cap-1; m1Ψ)

Item No. 43682

Product Insert (PDF)
Technical Information
Synonyms
  • Endoplasmic Reticulum-mScarlet mRNA (Cap-1; N1-Methylpseudouridine)
Emission
594 nm
Formulation
1 mM Sodium citrate, pH 6.4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    100 µg

    $504

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    1 mg

    $1,764

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    Cayman Chemical
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    Product Description

    ER-mScarlet probe mRNA (Cap-1; m1Ψ) encodes a fusion protein composed of an endoplasmic reticulum (ER) targeting sequence and mScarlet, a red fluorescent protein that displays absorbance and emission maxima of 569 and 594 nm, respectively.1 It is capped using a co-transcriptional capping method, resulting in the naturally occurring Cap-1 structure with high capping efficiency. ER-mScarlet probe mRNA is also polyadenylated and modified with N1-methylpseudouridine (m1Ψ) to reduce the host cell immune response and enhance mRNA stability. It can be used in the study of ER structure and function in live cells. Encapsulation of ER-mScarlet probe mRNA (Cap-1; m1Ψ) in lipid nanoparticles (LNPs) can be used for mRNA delivery and expression of ER-mScarlet.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bindels, D.S., Haarbosch, L., van Weeren, L., et al. mScarlet: A bright monomeric red fluorescent protein for cellular imaging. Nat. Methods 14(1), 53-56 (2017).