Our new Cayman LipiDOT Strips™ are a simple tool for the rapid identification of protein-lipid interactions. Researchers can screen a protein of interest against 22 biologically relevant lipids in one assay in a single day at a lower price compared with existing commercial options.

To promote bone growth, Cayman is developing our proprietary PGE2 analog in a drug-delivery matrix combination

Over the past 50 years, mass spectrometry has emerged as the gold standard for the quantitative analysis of bioactive lipids, including metabolites of arachidonic acid. Significant advances in mass analyzer hardware and ionization processes have brought this technique to the forefront. Important changes have occurred just in the past 25 years, with the emergence of electrospray ionization (ESI) and remarkable developments in tandem mass spectrometry, including tandem quadrupole mass spectrometer systems and ion trap-based mass analyzers.

Cayman offers an extensive library of agonists, antagonists, assays, and antibodies to study the function of Eicosanoid GPCRs. Explore the research products associated with each distinct signaling pathway.

Arachidonic acid undergoes enzymatic and non-enzymatic oxidation to produce an array of lipid metabolites

Learn about sphingolipid solubility, isolation, related fatty acid analysis by GC/FID, and storage and handling to achieve the best results possible with our sphingolipid products.

​Cayman’s state-of-the art mass spectrometry laboratories are equipped with several liquid chromatography- and gas chromatography-coupled systems, including triple quadrupole and high-resolution accurate mass Orbitrap mass spectrometers, enabling us to offer bioanalysis services customized for your specific needs. Your project is in the hands of experts who have many decades of collective experience in lipid synthesis, purification, and characterization. We sat down with one of those experts, Miguel Gijón, Ph.D., to talk about Cayman’s Lipidomic Profiling Services capabilities.

Cayman’s naming system for prostaglandins is taken from the literature, which often uses the trivial names and historically accepted conventions for the description of substituents (e.g., prostaglandins and their analogs).

Because of the shift in localization of lipid mediators from their tissues/cells of origin to the circulation and finally for excretion in urine, careful consideration of whole-body metabolism must be made when choosing specific sample types used for measurement.

Solubility functions by a group of rules that determine how dissolvable a substance (solute) is in solvent and depends entirely on the physical and chemical properties of the solute and solvent.

Whether you are new to lipids or a seasoned researcher, this collection of websites, databases, and software contains an abundance of resources to help you navigate lipid nomenclature and biology, develop laboratory protocols, and report data analyses.